Real Madrid vs Arsenal is the standout fixture of the Champions League quarter-final second legs, and it comes with high stakes and plenty of narrative.
Arsenal arrive at the Santiago Bernabeu with a stunning 3-0 advantage from the first leg, while 15-time European champions Real Madrid look to conjure another miracle comeback on home soil.
First Leg Shock: Arsenal Dominate Real Madrid
Few expected such a one-sided affair in the first leg at the Emirates Stadium, but Real Madrid vs Arsenal turned into a masterclass from the Gunners. Mikel Arteta’s side executed their game plan to perfection, with Declan Rice scoring two beautiful free-kicks and Mikel Merino—a makeshift striker—adding the third to stun Los Blancos.
Madrid’s famed midfield was overrun, their defense exposed, and the usually composed team completely lost control in the second half. The 3-0 loss means Madrid must now score at least three unanswered goals to force extra time and four to win outright—an almost impossible task, but not entirely out of the question for this magical Bernabeu stage.
RECOMMENDED:
Real Madrid Team News: Big Names Return, Big Misses Remain
As they prepare for the Real Madrid vs Arsenal clash, Carlo Ancelotti faces several selection headaches. Eduardo Camavinga is suspended after a needless red card in the first leg, while key defenders Dani Carvajal, Eder Militao, and Ferland Mendy remain out injured.
Kylian Mbappe, who was sent off in La Liga last weekend, is available as the ban doesn’t apply in European competition. He’ll start in attack alongside Jude Bellingham and Vinicius Junior, both of whom were rested during Madrid’s 1-0 win over Alaves. The atmosphere will be electric, but Madrid need more than energy—they need perfection.
Predicted Real Madrid lineup (4-2-3-1): Courtois; Valverde, Asencio, Rudiger, Alaba; Tchouameni, Modric; Rodrygo, Bellingham, Vinicius; Mbappe.
Arsenal Team News: Injuries to Key Stars, but Depth Showing
Heading into Real Madrid vs Arsenal, the Gunners are confident but cautious. Injuries have hit their squad, especially in defense, with Gabriel, Takehiro Tomiyasu, and Riccardo Calafiori ruled out. That forces Jakub Kiwior into the center-back role once again.
Arteta rested several key players in the weekend draw with Brentford, keeping them fresh for this massive clash. Martin Odegaard, Bukayo Saka, Jurrien Timber, and teenager Myles Lewis-Skelly are all expected to start.
Despite missing Kai Havertz and Gabriel Jesus, Arsenal have found a new formula with Merino up front. The Spaniard’s intelligent movement and link-up play have added a fresh dynamic to their attack.
Predicted Arsenal lineup (4-3-3): Raya; Timber, Saliba, Kiwior, Lewis-Skelly; Odegaard, Partey, Rice; Saka, Merino, Martinelli.
What to Expect in Real Madrid vs Arsenal
If there’s one thing the Champions League teaches us, it’s never to count Real Madrid out. Their home record in Europe, especially when chasing a comeback, is legendary. The crowd at the Bernabeu will create an intense, high-pressure environment from the first whistle.
But Arsenal’s game management has improved drastically under Arteta. They know how to absorb pressure and strike on the counter. With the pace of Martinelli and Saka, Madrid will have to be careful not to leave gaps as they push forward.
Expect Madrid to start fast, chasing an early goal to ignite the comeback. If Arsenal can weather the first 20–30 minutes, they’ll grow into the game and have chances of their own. The key battle will be in midfield, where Rice, Partey, and Odegaard will look to keep control and limit Modric and Bellingham’s influence.

Real Madrid vs Arsenal Prediction
Real Madrid will not go down without a fight. Their firepower and home advantage mean they are likely to score—but breaking Arsenal down multiple times is a different challenge.
Arsenal’s 3-0 cushion gives them flexibility. They don’t need to win or even draw; just avoid a heavy defeat. Given their form and composure, they should have enough to edge through.
Prediction: Real Madrid 2-1 Arsenal (Arsenal progress 4-2 on aggregate)
Key Stats Heading Into the Game
-
Arsenal have never lost to Real Madrid in official UEFA competition (2 wins, 1 draw).
-
Madrid have scored 3+ goals in 4 of their last 6 home games in the Champions League.
-
Arsenal are unbeaten in their last 8 away matches across all competitions.
-
Only four teams have overturned a 3-0 deficit in Champions League knockout history.